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The treatment options available for asthma, however, generally decrease chronic respiratory disease burden at a relatively low cost.IntroductionChronic respiratory diseases represent a major disease burden, with chronic obstructive respiratory disease (COPD) and asthma estimated to affect 64 million and 235 million people worldwide, respectively.1 In the latest estimates, COPD was the fourth leading cause of death in 2004, causing around three million deaths or 5.1% of all deaths in the world, and in 2030 it is projected to become the third leading cause, with 5.8 million or 8.6% of total deaths.1 Asthma morbidity and mortality account for around 1% of all disability adjusted life years (DALYs), equivalent to 16 million DALYs lost per year worldwide.1Much of the projected increase in COPD prevalence and mortality is closely associated with increases in tobacco smoking and exposure to indoor smoke from solid fuel for cooking and heating, as well as changing demographics in many countries.2 3 4 For asthma, the two main environmental risk factors are allergens and viral infections. Environmental risk factors associated with COPD are likely to disproportionately affect low and middle income countries, especially in Africa and Asia, which currently account for almost 90% of COPD deaths worldwide.5 6 7 8 According to the Global Burden of Disease study,9 the East Asia and Pacific region, primarily China, is the most affected in global terms, with 50% of the global annual mortality from COPD occurring there. The projected increase in the world's urban population from 45% to 59% by 202510 will likely lead to increased prevalence of chronic respiratory diseases worldwide, since urbanisation and adoption of Western lifestyle are major explanatory factors for increased asthma rates.A number of treatments are available for both conditions that can help control the symptoms and slow disease progression.
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